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Research Documents: Flavanol

  • Hurst, W.J., Stanley, B., Jan A. Glinski, J.A., Davey, M., Mark J. Payne, M.J., Stuart, D.A. Characterization of Primary Standards for Use in the HPLC Analysis of the Procyanidin Content of Cocoa and Chocolate Containing Products. Molecules, vol., p. 4136-4146, 2009.

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  • Ferreira, M.; Rocha, R.B.; Gonçalves, E.P.; Alves, E.U.; Ribeiro, G.D. Influência do substrato no crescimento de mudas de cupuaçu (Theobroma grandiflorum Schum.) = Influence of the substrate on the growth of cupuassu (Theobroma grandiflorum Schum.) seedlings. Acta Scientiarum:Agronomy, vol. 31, p. 677-681, 2009.

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  • Montaño Hernandez, P., Orozco Gutiérrez, J.J., Castillo Martínez, L., Orea Tejeda, A., Martínez, L., Cassis, N.L., Ubeda, F., Belio, G., Muñoz, E.C. Efecto de una bebida láctea a base de cocoa sobre la presión arterial y función endotelial en pacientes con insuficiencia cardiaca: ensayo clínico aleatorizado, doble ciego, controlado con placebo. Rev Cubana Cardiol Cir Cardiovasc, 17(1):52-61, 2011.

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  • Mullen, W., Borges, G., Donovan, J.L., Edwards, C.A., Serafinia, M., Lean, M. E.J., Crozier, A. Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. Am. J. Clin. Nutr., 2009, vol. 89, p. 1784–91.

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  • Rodríguez-Ramiro, I., Ramos, S., López-Oliva, E., Agis-Torres, A., Gómez-Juaristi, M., Mateos, R., Bravo, L., Goya, L., Martín, M.A. Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis. Mol. Nutr. Food Res. 2011 Sep 23. doi: 10.1002/mnfr.201100363. [Epub ahead of print].

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  • Egert, S., Rimbach, G. Which sources of flavonoids: Complex diets or dietary supplements? Adv. Nutr., vol. 2, p. 8-14, 2011.

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  • Danihelová, M., Šturdík, E. Flavonoid natural sources and their importance in the human diet. Potravinarstvo, vol. 5, No 4, p. 12-24, 2011.

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  • Van Praag, H,. Lucero, M.J., Yeo, G.W., Stecker, K., Heivand, N., Zhao, C., Yip, E., Afanador, M., Schroeter, H., Hammerstone, J., Gage, F.H. Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice. J. Neurosci., vol. 27(22), p. 5869-78. Erratum in: J Neurosci. 2007 Aug 1;27(31):ii.

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  • Mars Inc. Research finds flavanols in cocoa may help treat diabetes, strokes, and dementia. Press Release 25 July, 2005 (see above).

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  • Schroeter, H.; Heiss, C.; Balzar, J.; Kleinbongard, P.; Keen, C.L.; Hollenberg, N.K.; Slies, H.; Kwik-Uribe, C.; Schmitz, H.H.; Kelm, M. (–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proceedings Nat. Acad. Sci., vol. 103, p. 1024-1029. 2006.

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